FoxO3A Polyclonal Antibody, 20ul[BT-AP15669] Mammalian Expression Activated by phosphorylation at Thr-838|

Activated by phosphorylation at Thr-838| inhibited by phosphorylation at Ser-966 and Ser-1033

This protein contains a BAG domain near the C-terminus

C8 participates in the formation of the membrane attack complex (MAC)

AIFM1 encodes a flavoprotein essential for nuclear disassembly in apoptotic cells

FoxO3A Polyclonal Antibody, 20ul[BT-AP15669] Mammalian Expression Activated by phosphorylation at Thr-838|This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.