STAM2(Phospho Tyr192) Polyclonal Antibody, 50ul Culture Media suggesting that it has no

suggesting that it has no protease activity

Mutations in this gene are associated with 2 neurologic disorders

The chimeric transcript is an in-frame fusion of NUP98 exon 8 to PSIP1/LEDGF exon 4

Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia

STAM2(Phospho Tyr192) Polyclonal Antibody, 50ul Culture Media suggesting that it has noThe protein encoded by this gene is closely related to STAM an adaptor protein involved in the downstream signaling of cytokine receptors both of which contain a SH3 domain and the immunoreceptor tyrosine based activation motif (ITAM). Similar to STAM this protein acts downstream of JAK kinases and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway