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RN139 Rabbit Polyclonal Antibody, 20ul Diagnostic Probes & Oligos This gene encodes a neuron-restricted

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RN139 Rabbit Polyclonal Antibody, 20ul Diagnostic Probes & Oligos This gene encodes a neuron-restrictedThe protein encoded by this gene is a multi membrane spanning protein containing a RING H2 finger. This protein is located in the endoplasmic reticulum and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3: 8) translocation in a family with hereditary renal and non medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL

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Description

This gene encodes a neuron-restricted protein that contains a CRAL-TRIO motif common to proteins that bind small lipophilic molecules

while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1

The various isoforms have functional differences| with respect to ARF GAP activity and to G

The BinCARD gene maps to chromosome 9q22

RN139 Rabbit Polyclonal Antibody, 20ul Diagnostic Probes & Oligos This gene encodes a neuron-restrictedThe protein encoded by this gene is a multi membrane spanning protein containing a RING H2 finger. This protein is located in the endoplasmic reticulum and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3: 8) translocation in a family with hereditary renal and non medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL

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