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VATB2 Polyclonal Antibody, 20ul Immune Cell Analysis |subunit:Component of the NF-kappa-B p65-p50

SKU: 43139080814

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VATB2 Polyclonal Antibody, 20ul Immune Cell Analysis |subunit:Component of the NF-kappa-B p65-p50This gene encodes a component of vacuolar ATPase (V ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor mediated endocytosis, and synaptic vesicle proton gradient generation. V ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain

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Description

|subunit:Component of the NF-kappa-B p65-p50 complex

including K-562 (chronic myelogenous leukemia)

which result in multiple fusion proteins including EWS-ETV1 in Ewing sarcoma and at least 10 ETV1 partners (see PMID: 19657377

This protein may play a role in transcription-coupled DNA repair or genetic recombination

VATB2 Polyclonal Antibody, 20ul Immune Cell Analysis |subunit:Component of the NF-kappa-B p65-p50This gene encodes a component of vacuolar ATPase (V ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor mediated endocytosis, and synaptic vesicle proton gradient generation. V ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain

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