p27(Phospho Ser178) Polyclonal Antibody, 50ul Proteases FGFBP2 (fibroblast growth factor binding

FGFBP2 (fibroblast growth factor binding protein 2) encodes a member of the fibroblast growth factor binding protein family

This protein is thought to be involved in intracellular signal transduction mechanisms

Detected at very low levels in brain

Mutations in this gene result in one form of autosomal dominant hearing impairment

p27(Phospho Ser178) Polyclonal Antibody, 50ul Proteases FGFBP2 (fibroblast growth factor bindingThis gene encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The encoded protein binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from