TRI31 Polyclonal Antibody, 50ul Site-directed Mutagenesis ATXN7L3 contributes to a subcomplex

ATXN7L3 contributes to a subcomplex that specifically deubiquitinates both histones H2A and H2B

Was initially reported to contain ARM repeats (PubMed:11386760)

The protein encoded by this gene is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate| a metabolite of the histidine degradation pathway| to the folate pool

The encoded protein may regulate homeobox gene expression during anteroposterior patterning and hematopoiesis

TRI31 Polyclonal Antibody, 50ul Site-directed Mutagenesis ATXN7L3 contributes to a subcomplexThis gene encodes a protein that functions as an E3 ubiquitin protein ligase. This gene shows altered expression in certain tumors and may be a negative regulator of cell growth. Alternative splicing results in multiple transcript variants.